Erythema multiforme
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Erythema multiforme minor ― Ogow in xarumaha nabarada laga yaabo in ay bararaan.
Urticaria sidoo kale waxaa loo tixgelin karaa inay tahay cudur kala duwan.
References
Erythema multiforme (EM) waa xaalad ay baro bartilmaameed u eg ay ka soo baxaan maqaarka iyo xuubabka xuubka labadaba taasoo ay ugu wacan tahay falcelinta difaaca jirka. In kasta oo ay inta badan kiciyaan caabuqyada fayraska, gaar ahaan fayraska herpes simplex (HSV) , ama dawooyinka qaarkood, sababta ayaa ah mid aan la garanayn marar badan. Daawaynta EM ba'an waxay diiradda saartaa fududaynta calaamadaha iyadoo la isticmaalayo kiriimyo ay ku jiraan steroids ama antihistamines. Maareynta EM ee soo noqnoqota ayaa aad waxtar u leh marka loogu talagalay bukaan kasta. Hababka ugu horreeya waxay ku lug leeyihiin daawaynta afka iyo tan jirka labadaba. Kuwaas waxaa ka mid ah corticosteroids iyo daawooyinka fayraska. Daawaynta la mariyo waxa ay ka kooban tahay kareemyo isteeroydh oo xoog leh iyo xalalka xuubka xabkaha ee saameeya. Bukaannada aan ka jawaabin fayraska, fursadaha safka labaad waxaa ka mid ah daawooyinka difaaca jirka, antibiyootiga, anthelmintics, iyo antimalarials.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Xaalado badan, khafiif erythema multiforme ayaa keligiis ku baxa 2 ilaa 4 toddobaad gudahood. Stevens-Johnson syndrome, xaalad daran oo saameeya xuubabka xabka, waxay socon kartaa ilaa 6 toddobaad. Steroids caadi ahaan laguma taliyo kiisaska fudud. Haddii steroids loo isticmaalo erythema multiforme ee daran lama hubo maadaama aysan jirin natiijooyin cad oo ka soo baxay daraasado aan kala sooc lahayn oo muujinaya carruurta ka faa'iideysan doona daaweyntan.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Waxaan soo bandhigaynaa kiis afka ah erythema multiforme (EM) oo uu sababay TMP/SMX , oo muujinaya boogaha afka iyo faruuryaha ee caadiga ah oo aan lahayn nabarada maqaarka. Tani waxay hoosta ka xariiqaysaa baahida loo qabo in laga sooco cudurrada kale ee boogaha afka. Bukaanku wuxuu helay daaweynta calaamadaha iyo kiniinnada prednisolone, taasoo keentay horumar ka dib joojinta daaweynta TMP / SMX.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme waa falcelin ku lug leh maqaarka iyo mararka qaarkood xuubabka, oo uu kiciyo habka difaaca jirka. Caadi ahaan, waxay u muuqataa nabarro la beegsaday, kuwaas oo u muuqan kara kuwo go'doon ah, soo noqnoqda, ama sii socda. Nabarradani waxay caadi ahaan si siman u saameeyaan cidhifyada, gaar ahaan dusha sare. Sababaha ugu waaweyn waxaa ka mid ah caabuqyada sida fayraska herpes simplex iyo Mycoplasma pneumoniae, iyo sidoo kale daawooyinka qaarkood, tallaalada, iyo cudurrada difaaca jirka. Kala soocida erythema multiforme ee cudurka urtikaria waxay ku tiirsan tahay muddada nabarrada; erythema multiforme nabaradu waxay yihiin kuwo go'an ugu yaraan toddobo maalmood, halka nabarrada kaadi mareenku ay inta badan baaba'aan maalin gudaheed. Inkasta oo la mid ah, waxaa muhiim ah in la kala saaro erythema multiforme kan aadka u daran ee Stevens-Johnson syndrome, kaas oo sida caadiga ah soo bandhiga maqaarka erythematous baahsan ama finan leh finan. Maareynta erythema multiforme waxay ku lug leedahay nasinta calaamadaha isteeroid-ka jirka la mariyo ama antihistamines iyo wax ka qabashada sababta hoose. Kiisaska soo noqnoqda ee la xidhiidha fayraska herpes simplex, daawaynta ka hortagga fayraska ayaa lagula talinayaa. Ku lug lahaanshaha xuubka daran waxay u baahan kartaa isbitaal dhigista dareeraha xididada iyo beddelka elektrolytka.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Xaaladdu way kala duwan tahay fudfudud, finan isku xaddidan ilaa mid daran, qaab nafta halis gelisa oo loo yaqaan erythema multiforme major oo sidoo kale ku lug leh xuubabka xuubka. Duullaanka xuubka xabka ama joogitaanka bullaacu waa calaamadaha muhiimka ah ee darnaanta.
- Erythema multiforme minor: bartilmaameedyada caadiga ah ama kor loo qaaday, papules bararka ayaa si cad loo qaybiyey
Foomka khafiifka ah wuxuu badanaa keenaa cuncun fudud (laakiin cuncunku wuxuu noqon karaa mid aad u daran), finan casaan-cas ah, si siman loo habeeyey oo ka bilaabmaya cidhifyada. Xallinta finanka 7-10 maalmood gudahooda waa caadada qaabkan cudurka.
- Erythema multiforme major: bartilmaameedyada caadiga ah ama kor u kaca, papules bararka ayaa si cad loo qaybiyey iyada oo ku lug leh hal ama dhowr xuub xuubka. Goosashada Epidermal waxay ku lug leedahay wax ka yar 10% wadarta guud ee bedka jirka.
○ Daawaynta - Daawooyinka OTC
Haddii ay la socoto qandho (kor u kaca heerkulka jidhka), waxaa lagula talinayaa inaad booqato isbitaalka sida ugu dhakhsaha badan.
Daawooyinka laga shakiyo waa in la joojiyo. (tusaale, antibiyootiga, dawooyinka aan isteeroodka ee ka hortagga bararka)
Dawooyinka afka laga qaato sida cetirizine iyo loratadine ee cuncunka.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]